The International
HIV Controllers Study

Selected Reading Material

REFERENCES

Scheid, JF. et al. A method for identification of HIV gp 140 binding memory B cells in human blood. J Immunol Methods 2009.
Link to PubMed Abstract

Scheid, JF. et al. Broad diversity of neutralizaing antibodies isolated from memory B cells in HIV-infected individuals. Nature 2009.
Link to PubMed Abstract

Lambotte, O. et al. Heterogenous neutralizing antibody and antibody-dependent cell cytotoxicity responses in HIV-1 Elite Controllers. AIDS 2009.
Link to PubMed Abstract

O'Connell, KA. et al. The Role of Natural Killer Cells in a Cohort of Elite Suppressors: Low Frequency of the Protective KIR3DS1 Allele and Limited Inhibition of HIV-1 Replication in vitro. J Virol., 2009. Epub 2009.
Link to PubMed Abstract

Miura, T. et al. HLA-associated viral mutation are common in human immunodeficiency virus type 1 elite controllers. J Virol., 2009. Epub 2009.
Link to PubMed Abstract

Miura, T. et al. HLA-B57/B*5801 human immnodeficiency virus type 1 elite controllers select for rare gag variants associated with reduced viral replication capacity and strong cytotoxic T-lymphocyte recognition. J Virol., 2009. Epub 2008.
Link to PubMed Abstract

Ferre, AL. et al. Mucosal Immune Responses to HIV-1 in elite controllers: A potential correlate of immune control. Blood, 2008.
Link to PubMed Abstract

Walker, B. et al. Elite Control of HIV Infection: implications for vaccine design. Expert Opin Biol Ther., 2009.
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Mahalanabis, M. et al. Continuous Viral Escape and Selection by Autologous Neutralizing Antibodies in Drug-Naive HIV Controllers. J Virol., 2008. Epub 2008.
Link to PubMed Abstract

Miura, T. et al. HLA- associated alterations in replication capacity of chimeric NL4-3 viruses carrying a gag-protease from elite controllers of human immunodeficiency virus type 1. J Virol., 2009. Epub 2008.
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Hatano, H. et al. Evidence for persistent low-level viremia in individuals who control human immunodeficiency virus in the absence of antiretroviral therapy. J Virol., 2009. Epub 2008.
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Lichterfeld, M. et al. Telomerase activity of HIV-1-specific CD8+ T cells: Constitutive upregulation in controllers and selective increase by blockade of PD ligand 1 in progressors. Blood, 2008. Epub 2008.
Link to PubMed Abstract

Miura, T. et al. Genetic characterization of human immunodeficiency virus type 1 in elite controllers: lack of gross genetic defects or common amino acid changes. J Virol., 2008. Epub 2008.
Link to PubMed Abstract

Pereyra, F. et al. Genetic and immunologic heterogeneity among persons who control HIV infection in the absence of therapy. J Infect Dis., 2008. Epub 2008.
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Emu, B. et al. HLA class I-restricted T-cell responses may contribute to the control of human immunodeficiency virus infection, but such responses are not always necessary for long-term virus control. J Virol., 2008. Epub 2008.
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Saksena, N.K. et al. Elite HIV controllers: myth or reality? AIDS Rev., 2007.
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Hunt, P.W. et al. Relationship between T cell activation and CD4+ T cell count in HIV-seropositive individuals with undetectable plasma HIV RNA levels in the absence of therapy. J Infect Dis., 2008. Epub 2008.
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Deeks, S.G. et al. Human immunodeficiency virus controllers: mechanisms of durable virus control in the absence of antiretroviral therapy. Immunity, 2007. Review.
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Dolan, M.J. et al.CCL3L1 and CCR5 influence cell-mediated immunity and affect HIV-AIDS pathogenesis via viral entry-independent mechanisms. Nat Immunol., 2007. Epub, 2007.
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Sáez-Cirión, A. et al. HIV controllers: how do they tame the virus? Trends Immunol., 2007. Epub, 2007.
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Kaufmann, D.E. et al. Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction. Nat Immunol., 2007. Epub, 2007.
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Martin, M.P. et al. Innate partnership of HLA-B and KIR3DL1 subtypes against HIV-1. Nat Genet., 2007. Epub, 2007.
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Giraldo-Vela, J.P. et al. The Major Histocompatibility Complex class II alleles Mamu-DRB1*1003 and -DRB1*0306 are enriched in a cohort of SIV-infected rhesus macaque elite controllers. J Virol. 2007.
Link to PubMed Abstract

Potter S.J. et al. Preserved central memory and activated effector memory CD4+ T-cell subsets in human immunodeficiency virus controllers: an ANRS EP36 study. J Virol., 2007. Epub, 2007.
Link to PubMed Abstract

Honeyborne, I. et al. Control of human immunodeficiency virus type 1 is associated with HLA-B*13 and targeting of multiple gag-specific CD8+ T-cell epitopes. J Virol., 2007. Epub, 2007.
Link to PubMed Abstract

Kannanganat, S. et al. Human immunodeficiency virus type 1 controllers but not noncontrollers maintain CD4 T cells coexpressing three cytokines. J Virol., 2007. Epub, 2007.
Link to PubMed Abstract

Walker, B.D. Elite control of HIV Infection: implications for vaccines and treatment. Top HIV Med., 2007. Review.
Link to PubMed Abstract

Walker, B.D. HIV controllers: an untapped source of clues to overcoming HIV infection. Res Initiat Treat Action, 2007.
No abstract available.

Lamine, A. et al. Replication-competent HIV strains infect HIV controllers despite undetectable viremia (ANRS EP36 study). AIDS, 2007.
Link to PubMed Abstract

Sáez-Cirión, A. et al. HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype. Proc Natl Acad Sci USA, 2007. Epub, 2007.
Link to PubMed Abstract

Addo, M.M. et al. Fully differentiated HIV-1 specific CD8+ T effector cells are more frequently detectable in controlled than in progressive HIV-1 infection. PLoS ONE. 2007.
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Friedrich, T.C. et al. Subdominant CD8+ T-cell responses are involved in durable control of AIDS virus replication. J Virol., 2007. Epub 2007.
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Lambotte, O. et al. [HIV controllers: a homogeneous group of HIV-1 infected patients with a spontaneous control of viral replication]. Pathol Biol (Paris), 2006. Epub, 2006. French.
Link to PubMed Abstract

Huff, B. Who are the elite controllers? GMHC Treat Issues, 2005.
No abstract available.

Emu, B. et al. Phenotypic, functional, and kinetic parameters associated with apparent T-cell control of human immunodeficiency virus replication in individuals with and without antiretroviral treatment. J Virol., 2005.
Link to PubMed Abstract